Breast Reference Set Application: Anu Mathew-Meso Scale (2012)
- Abbreviated Name
- Breast Ref Set App: Mathew (2012)
- Lead Investigator
- Mathew, Anu — Meso Scale Diagnostics
- Coordinating Investigator
- Feng, Ziding — Fred Hutchinson Cancer Center
- Involved Investigators
Abstact
Aims
Using a subset of plasma samples (n=505) from the reference set, we analyzed 90 proteins by multiplexed immunoassays for their potential utility as diagnostic markers.
Analytic Method
Two vials of each sample (400 μl total volume) were provided to Meso Scale Diagnostics, LLC. (MSD®) for testing using a selection of MSD’s multiplexed assay panels. The samples were thawed and further aliquoted to strip-tubes before freezing on dry ice and storage at -80°C. This approach minimized the number of freeze-thaw cycles to no more than two for each sample.
Biomarkers
- ADIPOQ
- AFP
- AKR1B1
- AKR1C2
- ALPL
- ANXA1
- BCL2L2
- BGLAP
- CA125
- CA15-3
- CA19-9
- CCL11
- CCL13
- CCL17
- CCL2
- CCL22
- CCL26
- CCL4
- CCL5
- CDH1
- CDH3
- CEACAM5
- CHGA
- CRP
- CRYAB
- CSF1
- CXCL10
- CXCL8
- EGFR
- ERBB2
- FABP5
- FGF2
- FLT1
- FLT3LG
- GCLM
- GLO1
- GPI
- GSTM1
- GSTM2
- HGF
- ICAM1
- IFNG
- IL10
- IL12
- IL13
- IL18
- IL1B
- IL2
- IL4
- IL5
- KDR
- LBP
- MAGEA4
- MAPK14
- MBD1
- MET
- MMP1
- MMP10
- MMP2
- MMP3
- MMP9
- MSLN
- NECTIN4
- NME2
- ODC1
- Osteopontin
- PIGF
- PRDX4
- PRL
- PSA
- PSAT1
- PTPA
- RAC1
- S100A4
- S100A6
- SAA@
- SAT1
- SATL1
- SERPINB3
- SFN
- SOST
- TEK
- TIMP1
- TNF
- TNFRSF11B
- TNFRSF1A
- TNFRSF1B
- VCAM1
- VEGFC
- VEGFD
Data Collections
- No data available at this time for this protocol
Team Project
- Protocol ID
- 350
- Field of Research
- Proteomics
- Collaborative Group
- Breast and Gynecologic Cancers Research Group
- Cancer Types
-
- Malignant neoplasm of breast