| A blood-based proteomic classifier for the molecular characterization of pulmonary nodules. |
24132637 |
Sci Transl Med |
| A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. |
29622464 |
Cancer Cell |
| A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT. |
30487137 |
Cancer Res |
| A mesothelioma epidemic in Cappadocia: scientific developments and unexpected social outcomes. |
17251920 |
Nat Rev Cancer |
| A Multicenter Study of Volumetric Computed Tomography for Staging Malignant Pleural Mesothelioma. |
27596916 |
Ann Thorac Surg |
| A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples. |
29625054 |
Cell |
| A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily. |
30268436 |
Cell Syst |
| A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non-Small Cell Lung Cancer and Serum DNA. |
28855354 |
Clin Cancer Res |
| A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of BAP1 and Other Germline Mutations. |
30376426 |
J Clin Oncol |
| Aberrant methylation of p21 gene in lung cancer and malignant pleural mesothelioma. |
21709715 |
Acta Med Okayama |
| Aberrant promoter methylation of insulin-like growth factor binding protein-3 gene in human cancers. |
17096329 |
Int J Cancer |
| Airway Microbiota Is Associated with Upregulation of the PI3K Pathway in Lung Cancer. |
29864375 |
Am J Respir Crit Care Med |
| An extracellular signal-regulated kinase 2 survival pathway mediates resistance of human mesothelioma cells to asbestos-induced injury. |
21454801 |
Am J Respir Cell Mol Biol |
| An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. |
29625055 |
Cell |
| Asbestos exposure, pleural mesothelioma, and serum osteopontin levels. |
16221779 |
N Engl J Med |
| Assessment of Plasma Proteomics Biomarker's Ability to Distinguish Benign From Malignant Lung Nodules: Results of the PANOPTIC (Pulmonary Nodule Plasma Proteomic Classifier) Trial. |
29496499 |
Chest |
| Autoantibodies against tumor-associated antigens in the early detection of lung cancer. |
27565936 |
Lung Cancer |
| Autocrine CSF-1R signaling drives mesothelioma chemoresistance via AKT activation. |
24722292 |
Cell Death Dis |
| BAP1 regulates IP3R3-mediated Ca<sup>2+</sup> flux to mitochondria suppressing cell transformation. |
28614305 |
Nature |
| Biomarkers and molecular testing for early detection, diagnosis, and therapeutic prediction of lung cancer. |
23566973 |
Thorac Surg Clin |
| Biomarkers and prognostic factors for mesothelioma. |
23977535 |
Ann Cardiothorac Surg |
| Biomolecular and clinical practice in malignant pleural mesothelioma and lung cancer: what thoracic surgeons should know. |
24623168 |
Eur J Cardiothorac Surg |
| Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin. |
21159167 |
Mol Cancer |
| Blood-based lung cancer biomarkers identified through proteomic discovery in cancer tissues, cell lines and conditioned medium. |
26279647 |
Clin Proteomics |
| Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma. |
22552293 |
Cancer Res |
| CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells. |
24598827 |
PLoS One |
| Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. |
29625048 |
Cell |
| Cellular and molecular parameters of mesothelioma. |
16795078 |
J Cell Biochem |
| Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. |
29622466 |
Cancer Cell |
| Comparative Study of Autoantibody Responses between Lung Adenocarcinoma and Benign Pulmonary Nodules. |
26896032 |
J Thorac Oncol |
| Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients. |
30078747 |
Cancer Cell |
| Comprehensive Characterization of Cancer Driver Genes and Mutations. |
29625053 |
Cell |
| Comprehensive Characterization of Cancer Driver Genes and Mutations. |
30096302 |
Cell |
| Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer. |
30380420 |
Cell Rep |
| Comprehensive molecular profiling of lung adenocarcinoma. |
25079552 |
Nature |
| CREB-induced inflammation is important for malignant mesothelioma growth. |
25111229 |
Am J Pathol |
| Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters. |
16966607 |
Proc Natl Acad Sci U S A |
| Detection of integrin-linked kinase in the serum of patients with malignant pleural mesothelioma. |
21620418 |
J Thorac Cardiovasc Surg |
| Diagnosis and prognosis-review of biomarkers for mesothelioma. |
28706912 |
Ann Transl Med |
| Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma. |
19273703 |
J Clin Oncol |
| Differential N-Glycosylation Patterns in Lung Adenocarcinoma Tissue. |
26322380 |
J Proteome Res |
| Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung. |
15639718 |
Lung Cancer |
| DNA copy number gains in malignant pleural mesothelioma. |
26722325 |
Oncol Lett |
| DNA methylation profile of 28 potential marker loci in malignant mesothelioma. |
17659810 |
Lung Cancer |
| Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. |
29617662 |
Cell Rep |
| Early detection of malignant pleural mesothelioma in asbestos-exposed individuals with a noninvasive proteomics-based surveillance tool. |
23056237 |
PLoS One |
| Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma. |
21673066 |
Clin Cancer Res |
| Epigenetically regulated PAX6 drives cancer cells toward a stem-like state via GLI-SOX2 signaling axis in lung adenocarcinoma. |
29980786 |
Oncogene |
| ERK2 is essential for the growth of human epithelioid malignant mesotheliomas. |
21710492 |
Int J Cancer |
| Evaluation of clonal origin of malignant mesothelioma. |
25471750 |
J Transl Med |
| Exosomal miR-16-5p as a target for malignant mesothelioma. |
31406207 |
Sci Rep |
| Expression of Concern: HMGB1 and Its Hyperacetylated Isoform are Sensitive and Specific Serum Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients. |
32169964 |
Clin Cancer Res |
| Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implications. |
24669013 |
Ann Oncol |
| Extracellular mRNA Detected by Tethered Lipoplex Nanoparticle Biochip for Lung Adenocarcinoma Detection. |
27304243 |
Am J Respir Crit Care Med |
| Extracellular signal regulated kinase 5 and inflammasome in progression of mesothelioma. |
29416614 |
Oncotarget |
| Extracellular signal-regulated kinase 5: a potential therapeutic target for malignant mesotheliomas. |
23446998 |
Clin Cancer Res |
| Factors influencing malignant mesothelioma survival: a retrospective review of the National Mesothelioma Virtual Bank cohort. |
30410729 |
F1000Res |
| Fibulin-3 as a biomarker for pleural mesothelioma. |
23301743 |
N Engl J Med |
| Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma. |
23050525 |
N Engl J Med |
| Functional heterogeneity of osteopontin isoforms in non-small cell lung cancer. |
20689445 |
J Thorac Oncol |
| Genomic and Functional Approaches to Understanding Cancer Aneuploidy. |
29622463 |
Cancer Cell |
| Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. |
29617664 |
Cell Rep |
| Genomic events associated with progression of pleural malignant mesothelioma. |
18973227 |
Int J Cancer |
| Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. |
29617660 |
Cell Rep |
| Germline BAP1 mutations induce a Warburg effect. |
28665402 |
Cell Death Differ |
| Germline BAP1 mutations predispose to malignant mesothelioma. |
21874000 |
Nat Genet |
| Heparanase inhibitors restrain mesothelioma. |
30627323 |
Oncotarget |
| HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway. |
17872495 |
Am J Respir Cell Mol Biol |
| High Incidence of Somatic BAP1 alterations in sporadic malignant mesothelioma. |
25658628 |
J Thorac Oncol |
| High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma. |
27834213 |
Proc Natl Acad Sci U S A |
| HMGB1 and Its Hyperacetylated Isoform are Sensitive and Specific Serum Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients. |
26733616 |
Clin Cancer Res |
| HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma. |
28186988 |
Oncotarget |
| hsa-miR-29c* is linked to the prognosis of malignant pleural mesothelioma. |
20160038 |
Cancer Res |
| HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome. |
29311642 |
Oncogene |
| Identification of autoantibodies to ECH1 and HNRNPA2B1 as potential biomarkers in the early detection of lung cancer. |
28638733 |
Oncoimmunology |
| Identification of intelectin overexpression in malignant pleural mesothelioma by serial analysis of gene expression (SAGE). |
15777968 |
Lung Cancer |
| Increased osteonectin expression is associated with malignant transformation and tumor associated fibrosis in the lung. |
15246191 |
Lung Cancer |
| Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin. |
27486763 |
Oncotarget |
| Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma. |
28759042 |
Oncogene |
| Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. |
29617661 |
Cell Rep |
| Integrated Metabolomics and Proteomics Highlight Altered Nicotinamide- and Polyamine Pathways in Lung Adenocarcinoma. |
28049629 |
Carcinogenesis |
| Integrative Molecular Characterization of Malignant Pleural Mesothelioma. |
30322867 |
Cancer Discov |
| Involvement of Heparanase in the Pathogenesis of Mesothelioma: Basic Aspects and Clinical Applications. |
29579286 |
J Natl Cancer Inst |
| Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. |
28967920 |
Nat Med |
| lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. |
29622465 |
Cancer Cell |
| Lung cancer osteopontin isoforms exhibit angiogenic functional heterogeneity. |
19818970 |
J Thorac Cardiovasc Surg |
| Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. |
29617658 |
Cell Rep |
| Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. |
29625051 |
Cell |
| Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. |
22980975 |
Cell |
| Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects. |
19852844 |
Mol Cancer |
| MESOMARK: a potential test for malignant pleural mesothelioma. |
17289801 |
Clin Chem |
| Mesothelioma patients with germline BAP1 mutations have 7-fold improved long-term survival. |
25380601 |
Carcinogenesis |
| Mesothelioma: Scientific clues for prevention, diagnosis, and therapy. |
31283845 |
CA Cancer J Clin |
| MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. |
18093943 |
Proc Natl Acad Sci U S A |
| Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma. |
25657018 |
Cancer Prev Res (Phila) |
| Methylation profile landscape in mesothelioma: possible implications in early detection, disease progression, and therapeutic options. |
25421663 |
Methods Mol Biol |
| microRNAs derived from circulating exosomes as noninvasive biomarkers for screening and diagnosing lung cancer. |
23945385 |
J Thorac Oncol |
| Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers. |
29617665 |
Cell Rep |
| Molecular characterization of the peripheral airway field of cancerization in lung adenocarcinoma. |
25705890 |
PLoS One |
| Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma. |
31278276 |
Nat Commun |
| Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1. |
31257023 |
Cell |
| Nuclear estrogen receptor beta in lung cancer: expression and survival differences by sex. |
16243798 |
Clin Cancer Res |
| Nuclear, compared with combined nuclear and cytoplasmic expression of maspin, is linked in lung adenocarcinoma to reduced VEGF-A levels and in Stage I, improved survival. |
19309490 |
Histopathology |
| Oncogenic Signaling Pathways in The Cancer Genome Atlas. |
29625050 |
Cell |
| Onconase mediated NFKβ downregulation in malignant pleural mesothelioma. |
21317924 |
Oncogene |
| Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway. |
19047145 |
Cancer Res |
| Optical detection of buccal epithelial nanoarchitectural alterations in patients harboring lung cancer: implications for screening. |
20924114 |
Cancer Res |
| Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma. |
17493236 |
Histopathology |
| Overexpression of EPH receptor B2 in malignant mesothelioma correlates with oncogenic behavior. |
23887168 |
J Thorac Oncol |
| Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. |
29596783 |
Cell Syst |
| Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. |
29617668 |
Cell Rep |
| Pan-cancer analysis of whole genomes. |
32025007 |
Nature |
| Pathogenic Germline Variants in 10,389 Adult Cancers. |
29625052 |
Cell |
| Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors. |
28945830 |
Ann Oncol |
| Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells. |
22761781 |
PLoS One |
| Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. |
29625049 |
Cell |
| Plasma Anti-Glycan Antibody Profiles Associated with Nickel level in Urine. |
24737927 |
J Proteomics Bioinform |
| Plasma Biomarker Enrichment of Clinical Prognostic Indices in Malignant Pleural Mesothelioma. |
26903362 |
J Thorac Oncol |
| Plasma osteopontin velocity differentiates lung cancers from controls in a CT screening population. |
23568008 |
Cancer Biomark |
| Positive nuclear BAP1 immunostaining helps differentiate non-small cell lung carcinomas from malignant mesothelioma. |
27447750 |
Oncotarget |
| Prediction of lung cancer using volatile biomarkers in breath. |
17522431 |
Cancer Biomark |
| Pro-tumorigenic effects of miR-31 loss in mesothelioma. |
20463022 |
J Biol Chem |
| Processing and analysis of serum antibody binding signals from Printed Glycan Arrays for diagnostic and prognostic applications. |
22112531 |
Int J Bioinform Res Appl |
| Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation. |
20616036 |
Proc Natl Acad Sci U S A |
| Proteomic profiling of lung adenocarcinoma indicates heightened DNA repair, antioxidant mechanisms and identifies LASP1 as a potential negative predictor of survival. |
27799870 |
Clin Proteomics |
| Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma. |
24240684 |
Oncogene |
| Reduction of elevated plasma osteopontin levels with resection of non-small-cell lung cancer. |
20085934 |
J Clin Oncol |
| Serum concentration of integrin-linked kinase in malignant pleural mesothelioma and after asbestos exposure. |
23045294 |
Eur J Cardiothorac Surg |
| Serum mesothelin for diagnosing malignant pleural mesothelioma: an individual patient data meta-analysis. |
22412141 |
J Clin Oncol |
| Serum phosphatidylethanolamine levels distinguish benign from malignant solitary pulmonary nodules and represent a potential diagnostic biomarker for lung cancer. |
27002763 |
Cancer Biomark |
| Soluble mesothelin-related peptide level elevation in mesothelioma serum and pleural effusions. |
18154821 |
Ann Thorac Surg |
| Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types. |
29617667 |
Cell Rep |
| Stage Dependence, Cell-Origin Independence, and Prognostic Capacity of Serum Glycan Fucosylation, β1-4 Branching, β1-6 Branching, and α2-6 Sialylation in Cancer. |
29129073 |
J Proteome Res |
| SV40 detection in human tumor specimens. |
16267039 |
Cancer Res |
| Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines. |
19960346 |
Cancer Chemother Pharmacol |
| Telomerase activity in pleural malignant mesotheliomas. |
21277646 |
Lung Cancer |
| The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas. |
18949431 |
Oncol Rep |
| The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. |
29617669 |
Cell Rep |
| The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. |
29925010 |
Cell Rep |
| The Immune Landscape of Cancer. |
29628290 |
Immunity |
| The Microbiome in Lung Cancer Tissue and Recurrence-Free Survival. |
30733306 |
Cancer Epidemiol Biomarkers Prev |
| The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival. |
20010871 |
Oncogene |
| Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma. |
29362358 |
Oncogenesis |
| Tissue and exosomal miRNA editing in Non-Small Cell Lung Cancer. |
29976955 |
Sci Rep |
| TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis. |
16798876 |
Proc Natl Acad Sci U S A |
| Tsc1-Tp53 loss induces mesothelioma in mice, and evidence for this mechanism in human mesothelioma. |
23851502 |
Oncogene |
| Tumorigenic properties of alternative osteopontin isoforms in mesothelioma. |
19285954 |
Biochem Biophys Res Commun |
| Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer. |
21170350 |
PLoS One |
| Validation of a blood protein signature for non-small cell lung cancer. |
25114662 |
Clin Proteomics |
| Validation of a multiprotein plasma classifier to identify benign lung nodules. |
25590604 |
J Thorac Oncol |
| Variant Ciz1 is a circulating biomarker for early-stage lung cancer. |
23074256 |
Proc Natl Acad Sci U S A |
| When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All? |
30863365 |
Front Endocrinol (Lausanne) |
| Whole blood FPR1 mRNA expression predicts both non-small cell and small cell lung cancer. |
29313979 |
Int J Cancer |
| Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma. |
25488749 |
Cancer Res |
| Withaferin A inhibits the proteasome activity in mesothelioma in vitro and in vivo. |
22912669 |
PLoS One |
