Pancreatic Cystic Fluid Reference Set
- Abbreviated Name
- Panc Cyst
- Lead Investigator
- Brand, Randall E. — University of Pittsburgh
- Coordinating Investigator
- Feng, Ziding — Fred Hutchinson Cancer Center
- Involved Investigators
-
- Feng, Ziding — Fred Hutchinson Cancer Center
- Park, Walter — Stanford University
- DiMaio, Christopher — Mount Sinai Medical Center
- Brand, Randall E. — University of Pittsburgh
- Diaz-Mayoral, Norma — Frederick National Laboratory for Cancer Research
- Srivastava, Sudhir — National Cancer Institute
- Allen, Peter J. — Duke University
- Simeone, Diane M. — University of Michigan
Abstact
The proposed reference set will be designed to evaluate biomarkers for the following applications aimed at determining whether a patient would benefit from surgical resection of their cystic lesion: 1. Distinguish between pancreatic cysts that have high-malignant potential and cysts that have low or no malignant potential at time of endoscopic ultrasound evaluation. a. By analysis of blood b. By analysis of pancreatic cystic fluid 2. Distinguish between cysts that have any malignant potential (high and low) and cysts that have no malignant potential (benign lesions) at time of endoscopic ultrasound evaluation. a. By analysis of blood b. By analysis of pancreatic cystic fluid 3. Distinguish between a cyst that is mucinous (malignant potential) or non-mucinous (no malignant potential) at time of endoscopic ultrasound evaluation. a. By analysis of blood b. By analysis of pancreatic cystic fluid 4. Distinguish between pancreatic cysts that have high-malignant potential and cysts that have low or no malignant potential at time of evaluation in surgery clinic. a. By analysis of blood 5. Distinguish between cysts that have any malignant potential (high and low) and cysts that have no malignant potential (benign lesions) at time of evaluation in surgery clinic. a. By analysis of blood 6. Distinguish between a cyst that is mucinous (malignant potential) or non-mucinous (no malignant potential) at time of evaluation in surgery clinic. a. By analysis of blood If successful in meeting these afore-mentioned objectives, these results can then be used in the development of future studies at identifying the need for additional evaluation (i.e., endoscopic ultrasound with fine needle aspiration) of an incidental cyst
Aims
see Objectives
Analytic Method
N/A
Biomarkers
- No biomarkers available at this time for this protocol
Data Collections
- No data available at this time for this protocol
Team Project
- Protocol ID
- 342
- Protocol Type
- Reference Set
- Field of Research
- Other, Specify
- Collaborative Group
- G.I. and Other Associated Cancers Research Group
- Cancer Types
-
- Malignant neoplasm of pancreas