Roy, Hemant K.

Open Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Light Scattering Spectroscopy for the Detection of Colorectal Neoplasia Involved 0 0
Spectral Markers for Early Detection of Colon Neoplasia Coordinating 0 0

Closed Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Prevalidation for Rectal PWS for Colon Cancer Screening Leading 1 0


Publication NamePubMed IDJournal
Assessment of blood supply in superficial tissue by polarization-gated elastic light-scattering spectroscopy. 16422163 Appl Opt
Association of stem-like cells in gender-specific chemoprevention against intestinal neoplasia in MIN mouse. 21769438 Oncol Rep
Associations between the age at diagnosis and location of colorectal cancer and the use of alcohol and tobacco: implications for screening. 16567601 Arch Intern Med
Biomarkers for the early detection of cancer: an inflammatory concept. 17893302 Arch Intern Med
Chemoprevention of colon carcinogenesis by polyethylene glycol: suppression of epithelial proliferation via modulation of SNAIL/beta-catenin signaling. 16928827 Mol Cancer Ther
Colon cancer screening: the good, the bad, and the ugly. 17101934 Arch Intern Med
Colonoscopy and optical biopsy: bridging technological advances to clinical practice. 21521641 Gastroenterology
Depth-resolved low-coherence enhanced backscattering. 15832924 Opt Lett
Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: modulation of apoptosis, proliferation, and fractal dimension. 15367710 Mol Cancer Ther
Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation. 15961079 FEBS Lett
Four-dimensional elastic light-scattering fingerprints as preneoplastic markers in the rat model of colon carcinogenesis. 15057746 Gastroenterology
Increased microvascular blood content is an early event in colon carcinogenesis. 15831911 Gut
Inducible nitric oxide synthase (iNOS) mediates the early increase of blood supply (EIBS) in colon carcinogenesis. 17658518 FEBS Lett
Involvement of p21cip1/waf1 in the anti-proliferative effects of polyethylene glycol in colon carcinogenesis. 21170505 Int J Oncol
Light-scattering technologies for field carcinogenesis detection: a modality for endoscopic prescreening. 21078318 Gastroenterology
Low-coherence enhanced backscattering: review of principles and applications for colon cancer screening. 16965153 J Biomed Opt
Low-coherent backscattering spectroscopy for tissue characterization. 15717826 Appl Opt
Moving toward personalization of colorectal cancer screening: Comment on "Influence of race and sex on prevalence and recurrence of colon polyps". 20625019 Arch Intern Med
Nanocytology for field carcinogenesis detection: novel paradigm for lung cancer risk stratification. 21174531 Future Oncol
Neo-angiogenesis and the premalignant micro-circulatory augmentation of early colon carcinogenesis. 21493000 Cancer Lett
Optical detection of buccal epithelial nanoarchitectural alterations in patients harboring lung cancer: implications for screening. 20924114 Cancer Res
Optical markers in duodenal mucosa predict the presence of pancreatic cancer. 17671121 Clin Cancer Res
Optical measurement of rectal microvasculature as an adjunct to flexible sigmoidosocopy: gender-specific implications. 20570881 Cancer Prev Res (Phila)
Polyethylene glycol inhibits intestinal neoplasia and induces epithelial apoptosis in Apc(min) mice. 15374630 Cancer Lett
Practicing medicine at the front lines of the genomic revolution. 16157823 Arch Intern Med
Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling: Influence of smoking. 16874859 World J Gastroenterol
Risk stratification of colon carcinogenesis through enhanced backscattering spectroscopy analysis of the uninvolved colonic mucosa. 16467111 Clin Cancer Res
Spectral markers in preneoplastic intestinal mucosa: an accurate predictor of tumor risk in the MIN mouse. 16030095 Cancer Epidemiol Biomarkers Prev
The association between aspirin use and the incidence of colorectal cancer in women. 16847042 Am J Epidemiol
The nonsteroidal anti-inflammatory drug, nabumetone, differentially inhibits beta-catenin signaling in the MIN mouse and azoxymethane-treated rat models of colon carcinogenesis. 15617833 Cancer Lett
The transcriptional repressor SNAIL is overexpressed in human colon cancer. 15712635 Dig Dis Sci
Tobacco use and increased colorectal cancer risk in patients with hereditary nonpolyposis colorectal cancer (Lynch syndrome). 15596632 Arch Intern Med


Biomarkers of Colon cancer
We are currently involved in the development of spectral signatures as a marker for the "field effect" of colon carcinogenesis. We believe that this will enable risk stratification
Sprectral Markers for Colon Carcinogenesis Detection
Our group is interested in using novel light scattering approaches to detect field changes of colon carcinogenesis and hence allow risk stratification of colon carcinogenesis

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Photograph of Roy, Hemant K.
Boston University
Person ID
EDRN Title
EDRN Associate Member
To update contact information, please visit the Data Management and Coordinating Center .