Canary Prostate Active Surveillance Study: design of a multi-institutional active surveillance cohort and biorepository.


Active surveillance is a management plan for localized prostate cancer that offers selective delayed intervention on indication of disease progression, allowing patients to delay or avoid treatment and associated side-effects. Outcomes from centers that promote active surveillance are favorable, with high rates of disease-specific survival. However, there remains a need for prognostic variables or biomarkers that distinguish with high specificity the aggressive cancers that progress on surveillance from the indolent cancers. The Canary Prostate Active Surveillance Study is a multicenter study and a biorepository that will discover and confirm biomarkers of aggressive disease as defined by histologic, prostate-specific antigen, or clinical criteria.

  • Brooks JD
  • Carroll PR
  • Feng Z
  • Gleave ME
  • Lin DW
  • Nelson PS
  • Newcomb LF
  • Thompson IM
PubMed ID
Appears In
Urology, 2010, 75 (2)