Computational Proteomics Analysis System (CPAS): an extensible, open-source analytic system for evaluating and publishing proteomic data and high throughput biological experiments.
Abstact
The open-source Computational Proteomics Analysis System (CPAS) contains an entire data analysis and management pipeline for Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) proteomics, including experiment annotation, protein database searching and sequence management, and mining LC-MS/MS peptide and protein identifications. CPAS architecture and features, such as a general experiment annotation component, installation software, and data security management, make it useful for collaborative projects across geographical locations and for proteomics laboratories without substantial computational support.
Authors
- Bellew M
- Detter A
- Eng J
- Faca V
- Fang R
- Fitzgibbon M
- Gafken P
- Hanash S
- Holzman T
- Hussey P
- Igra M
- Lin CW
- Maclean B
- McIntosh MW
- Paulovich A
- Rauch A
- States D
- Whiteaker J
- Zhang H