BDL Esophageal Biomarker Development
- Abbreviated Name
- BDL Esophageal Biomarker Development
- Lead Investigator
- Markowitz, Sanford — Case Western Reserve University
- Coordinating Investigator
- No coordinating investigator
- Involved Investigators
Abstact
Prospective enrollment of individuals referred for upper endoscopy who will undergo comparison esophageal sampling with an esophageal balloon device and analysis of methylated DNA biomarkers for detection of Barrett’s esophagus.
Aims
Evaluation of methylated DNA for detection of Barrett’s esophagus on samples retrieved by an esophageal balloon
Analytic Method
No analytic method available.
Publications
- Aberrant vimentin methylation is characteristic of upper gastrointestinal pathologies.
- Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus.
Biomarkers
Data Collections
- No data collections available at this time for this protocol.
Team Project
- Start Date
- Jan 1 2011
- Protocol ID
- 488
- Protocol Type
- Single
- Field of Research
- Epigenomics
- Collaborative Group
- G.I. and Other Associated Cancers Research Group
- Cancer Types
-
- Malignant neoplasm of colon