A Urine Exosome Gene Expression Panel Distinguishes between Indolent and Aggressive Prostate Cancers at Biopsy

Abbreviated Name

PCGEM1 and PCA3 noncoding RNAs

Lead Investigator

Chesnut, Gregory — Center for Prostate Disease Research Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center

Coordinating Investigator

Chesnut, Gregory — Center for Prostate Disease Research Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center

Involved Investigators

Chesnut, Gregory — Center for Prostate Disease Research Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center

Abstact

Aims

1. To present the development and optimization of a noninvasive, first catch, nonDRE urine based sensitive gene expression assay 2. To define a CaP gene panel that can discriminate GS 7-10 from GS 6 (3D3) and benign disease before biopsy; IRB #WU IRB No. 11-7487

Analytic Method

ddPCR

Biomarkers

No biomarkers available at this time for this protocol

Data Collections

No data available at this time for this protocol

Team Project

Protocol ID

484

Field of Research

Genomics

Collaborative Group

Prostate and Urologic Cancers Research Group

Cancer Types

Malignant neoplasm of prostate

Phased Status