BRSCW Reference Set Application: Karen Abbott -University of Arkansas (2014)

Abbreviated Name
BRSCW Ref Set App: Abbott (2014)
Lead Investigator
Abbott, KarenFlorida International University
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators

Abstact

See objectives

Aims

We would like to used pooled reference samples to develop a sensitive magnetic bead-based assay to detect these glycoproteins with bisecting and core fucosylation changes. We have purified fusion-tagged glycoproteins with the specific glycan structures that we will spike into the control samples to determine the range and variation of detection prior to the phase II sample analysis. We will also measure the variance between the malignant ovarian cancer pooled samples and control benign pooled samples to determine if the assay can measure statistically significant differences.

Analytic Method

Data will be analyzed by the DMCC

Publications

  • No publications available at this time for this protocol.

Biomarkers

  • No biomarkers available at this time for this protocol.

Data Collections

  • No data collections available at this time for this protocol.
 Team Project
Finish Date
Jul 19 2015
Protocol ID
395
Protocol Type
Reference Set
Field of Research
Glycomics
Collaborative Group
Breast and Gynecologic Cancers Research Group
Cancer Types
  • Malignant neoplasm of breast
Phased Status
1

Associated Forms