MSA Bladder Reference Set Application: Charles Rosser-Hawaii (2014)

Abbreviated Name
MSA Bladder Ref Set App: Rosser (2014)
Lead Investigator
Rosser, Charles JUniversity of Hawaii Cancer Center
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators



Discovery cohort - 200 DNA samples from exfoliated cells (100 BCa and 100 controls) from a reference set at EDRN will be screened via direct PCR and sequencing for mutations with PAI-1 (promoter and exons 1-9) and ANG (promoter and exons 1-3).

Analytic Method

Mutational analysis will be assessed using Ion Reporter™ Software located in our Genomic Shared Resource. Fisher’s exact test will be used to assess the association of PAI-1 and ANG genetic alterations with clinicopathologic factors or mutations with each other. A P-value of < 0.05 will be considered to be statistically significant.


Data Collections

  • No data available at this time for this protocol
 Team Project
Protocol ID
Protocol Type
Reference Set
Field of Research
Collaborative Group
Prostate and Urologic Cancers Research Group
Cancer Types
  • Malignant neoplasm of bladder

Associated Forms