MSA Bladder Reference Set Application: Charles Rosser-Hawaii (2014)

Abbreviated Name
MSA Bladder Ref Set App: Rosser (2014)
Lead Investigator
Rosser, Charles JUniversity of Hawaii Cancer Center
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators

Abstact

Aims

Discovery cohort - 200 DNA samples from exfoliated cells (100 BCa and 100 controls) from a reference set at EDRN will be screened via direct PCR and sequencing for mutations with PAI-1 (promoter and exons 1-9) and ANG (promoter and exons 1-3).

Analytic Method

Mutational analysis will be assessed using Ion Reporter™ Software located in our Genomic Shared Resource. Fisher’s exact test will be used to assess the association of PAI-1 and ANG genetic alterations with clinicopathologic factors or mutations with each other. A P-value of < 0.05 will be considered to be statistically significant.

Biomarkers

Data Collections

  • No data available at this time for this protocol
 Team Project
Protocol ID
394
Protocol Type
Reference Set
Field of Research
Genomics
Collaborative Group
Prostate and Urologic Cancers Research Group
Cancer Types
  • Malignant neoplasm of bladder

Associated Forms