Liver Rapid Reference Set Application: Gary Norman-INOVA (2012)
- Abbreviated Name
- Liver Rapid Ref Set App: Norman (2012)
- Lead Investigator
- Norman, Gary L. — INOVA Diagnostics Inc.
- Coordinating Investigator
- Feng, Ziding — Fred Hutchinson Cancer Center
- Involved Investigators
Abstact
No abstract availalbe.
Aims
The EDRN reference set will provide us with an opportunity to test the present version of the assay on a new, well-characterized cohort that has not been subjected to multiple freeze/thaw cycles.
Analytic Method
Since this assay will be submitted to the FDA for 510(k) clearance, we will want to test a training set prior to the blinded test set. Statistical analysis will be conducted at the DMCC.
Outcome
We have developed a new and novel assay for the detection of Golgi protein 73 (GP73), also known as Golgi membrane protein 1 (Golm1) or Golgi phosphoprotein 2 (Golph2), in serum/plasma. The clinical question is to determine the clinical utility of gp73 antigen detection by the new assay for early hepatocullular carcinoma (HCC) diagnosis, for risk-assessment of patients at high risk for progression of their liver disease, and for prognosis.
Publications
- No publications available at this time for this protocol.
Biomarkers
Data Collections
- No data collections available at this time for this protocol.
Team Project
- Start Date
- Jul 12 2012
- Estimated Finish Date
- Sep 12 2012
- Finish Date
- Sep 30 2012
- Protocol ID
- 356
- Protocol Type
- Reference Set
- Field of Research
- Proteomics
- Collaborative Group
- G.I. and Other Associated Cancers Research Group
- Cancer Types
-
- Liver cell carcinoma
- Phased Status
- 1