YES
- Aliases
-
- C-YES
- Cellular Yes-1 Protein
- HsT441
- P61-YES
- Proto-Oncogene C-Yes
- Proto-Oncogene Tyrosine-Protein Kinase YES
- Tyrosine-Protein Kinase Yes
- V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1
- YES
- YES1
- Yamaguchi Sarcoma Oncogene
- Description
- YES1, also known as YES, is a non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. It is the cellular homolog of the Yamaguchi sarcoma virus oncogene and belongs to the src family of proteins. YES1 is involved in many phosphorylation reactions, including a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- YES1
- Certifications
-
- None
- QA State for Lung
- Curated
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.