XRCC5

Aliases:
This biomarker is also known as:
  • X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5 (Double-Strand-Break Rejoining; Ku Autoantigen, 80kD)
  • CTCBF
  • Thyroid-Lupus Autoantigen
  • KARP1
  • X-Ray Repair Cross-Complementing Protein 5
  • NFIV
  • Ku Autoantigen
  • CTC Box-Binding Factor 85 KDa Subunit
  • Ku86 Autoantigen Related Protein 1
  • XRCC5
  • DNA Repair Protein XRCC5
  • 86 KDa Subunit Of Ku Antigen
  • 80kDa
  • TLAA
  • KU80
  • ATP-Dependent DNA Helicase II 80 KDa Subunit
  • Nuclear Factor IV
  • CTC85
  • Lupus Ku Autoantigen Protein P86
  • X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5 (Double-Strand-Break Rejoining)
  • Ku Autoantigen, 80kDa
  • KARP-1
  • Ku80
  • KUB2
  • ATP-Dependent DNA Helicase 2 Subunit 2
  • Ku86
  • G22P2
  • EC 3.6.4.-

Description…

From NCBI Entrez Gene: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: XRCC5

The following organs have data associated with this biomarker…

Attributes

Phase: 1
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0