Aliases

• EC 6.3.2.-
• RFP
• RFP transforming protein
• RING finger protein 76
• RNF76
• Ret finger protein
• TRIM27
• Tripartite motif-containing protein 27
• ret finger protein
• tripartite motif containing 27
• tripartite motif protein TRIM27
• tripartite motif-containing 27
• tripartite motif-containing protein 27
• zinc finger protein RFP

Description

From NCBI Gene: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq, Jul 2008]

Attributes

QA State

Under Review

Type

Gene

HGNC Name

TRIM27