TRAF3IP2

Aliases:
This biomarker is also known as:
  • chromosome 6 open reading frame 5
  • TRAF3-interacting protein 2
  • TRAF3 interacting protein 2
  • DKFZP586G0522
  • PSORS13
  • ACT1
  • CIKS
  • nuclear factor NF-kappa-B activator 1
  • C6orf4
  • chromosome 6 open reading frame 2
  • C6orf5
  • Nuclear factor NF-kappa-B activator 1
  • NFkB-activating protein ACT1
  • TRAF3IP2
  • C6orf6
  • adapter protein CIKS
  • Connection to IKK and SAPK/JNK
  • connection to IKK and SAPK/JNK
  • C6orf2

Description…

From NCBI Gene: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: TRAF3IP2

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0