TEK

Aliases
  • CD202B
  • CD202b antigen
  • EC 2.7.10.1
  • Endothelial tyrosine kinase
  • TEK
  • TEK tyrosine kinase, endothelial
  • TIE-2
  • TIE2
  • Tunica interna endothelial cell kinase
  • Tyrosine kinase with Ig and EGF homology domains-2
  • Tyrosine-protein kinase receptor TEK
  • Tyrosine-protein kinase receptor TIE-2
  • VMCM
  • VMCM1
  • angiopoietin-1 receptor
  • endothelial tyrosine kinase
  • hTIE2
  • p140 TEK
  • soluble TIE2 variant 1
  • soluble TIE2 variant 2
  • tunica interna endothelial cell kinase
  • tyrosine kinase with Ig and EGF homology domains-2
  • tyrosine-protein kinase receptor TEK
  • tyrosine-protein kinase receptor TIE-2
  • venous malformations, multiple cutaneous and mucosal
Description
From NCBI Gene: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Attributes
QA State
Under Review
Type
Protein
HGNC Name
TEK
Certifications
  • None
QA State for Breast
Curated

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.