TEK

Aliases:
This biomarker is also known as:
  • EC 2.7.10.1
  • TIE2
  • endothelial tyrosine kinase
  • VMCM1
  • CD202b antigen
  • p140 TEK
  • TEK tyrosine kinase, endothelial
  • Tyrosine-protein kinase receptor TIE-2
  • angiopoietin-1 receptor
  • soluble TIE2 variant 2
  • Endothelial tyrosine kinase
  • TIE-2
  • hTIE2
  • tyrosine-protein kinase receptor TIE-2
  • TEK
  • tunica interna endothelial cell kinase
  • VMCM
  • Tunica interna endothelial cell kinase
  • Tyrosine-protein kinase receptor TEK
  • Tyrosine kinase with Ig and EGF homology domains-2
  • soluble TIE2 variant 1
  • CD202B
  • tyrosine kinase with Ig and EGF homology domains-2
  • tyrosine-protein kinase receptor TEK
  • venous malformations, multiple cutaneous and mucosal

Description…

From NCBI Gene: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: TEK

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0