SOD1
- Aliases
-
- ALS
- ALS1
- Cu,Zn superoxide dismutase, EC 1.15.1.1.
- Cu/Zn superoxide dismutase
- EC 1.15.1.1
- IPOA
- SOD
- SOD, soluble
- SOD1
- Superoxide dismutase 1
- amyotrophic lateral sclerosis 1 (adult)
- hSod1
- homodimer
- indophenoloxidase A
- superoxide dismutase 1, soluble
- superoxide dismutase [Cu-Zn]
- superoxide dismutase, cystolic
- Description
- SOD1, superoxide dismutase, is one of two isozymes that destroy free superoxide radicals that are normally produced within the cells and which are toxic to biological systems. The SOD1 isozyme is a soluble homodimer found in the cytoplasm. It converts naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1, a familial form of amyotrophic lateral sclerosis.
Attributes
- QA State
- Under Review
- Type
- Gene
- HGNC Name
- SOD1
- Certifications
-
- None
- QA State for Lung
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.