SFTPB

Aliases
  • 18 kDa pulmonary-surfactant protein
  • 6 kDa protein
  • PSP-B
  • Pulmonary surfactant-associated proteolipid SPL(Phe)
  • SFTB3
  • SFTP3
  • SFTPB
  • SMDP1
  • SP-B
  • pulmonary surfactant-associated protein B
  • pulmonary surfactant-associated proteolipid SPL(Phe)
  • surfactant protein B
  • surfactant, pulmonary-associated protein B
Description
SFTPB, or pulmonary-associated surfactant protein B, is an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. These proteins are composed of 90% lipids and 10% proteins, and include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. There are several alternatively spliced transcript variants for this gene, all encoding the same protein.
Attributes
QA State
Under Review
Type
Protein
HGNC Name
SFTPB
Certifications
  • None
QA State for Lung
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.