SERPIND1
- Aliases
-
- D22S673
- HC-II
- HC2
- HCF2
- HCII
- HLS2
- Heparin Cofactor 2
- Heparin Cofactor II
- Heparin Cofactor II Splice Isoform
- LS2
- Leuserpin 2
- Protease Inhibitor Leuserpin-2
- SERPIND1
- Serine (Or Cysteine) Proteinase Inhibitor, Clade D (Heparin Cofactor), Member 1
- Serpin D1
- Serpin Family D Member 1
- Serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1
- THPH10
- Description
- From NCBI Gene: This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015]
Attributes
- QA State
- Under Review
- Type
- Protein
- HGNC Name
- SERPIND1
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.