SERPINA1
- Aliases
-
- A1A
- A1AT
- AAT
- Alpha-1 protease inhibitor
- Alpha-1-antiproteinase
- MGC23330
- MGC9222
- PI
- PI1
- PRO2275
- SERPINA1
- Serpin A1
- alpha-1-antitrypsin
- alpha-1-antitrypsin null
- alpha1AT
- hAAT
- protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin
- serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
- serine (or cysteine) proteinase inhibitor, clade A, member 1
- serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
- Description
- Alpha-1-antitrypsin is secreted and is an extracellular serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Elevation of alpha1-AT serum levels have been observed in the course of a large number of malignant diseases. Several transcript variants encoding the same protein have been found for this gene.
Attributes
- QA State
- Under Review
- Type
- Protein
- HGNC Name
- SERPINA1
- Certifications
-
- None
- QA State for Bladder
- Curated
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Certifications
-
- None
- QA State for Liver
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Certifications
-
- None
- QA State for Lung
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.