Aliases

• APC
• Activated Protein C
• Anticoagulant Protein C
• Autoprothrombin IIA
• Blood Coagulation Factor XIV
• PC
• PROC
• PROC1
• Prepro-Protein C
• Protein C (Inactivator Of Coagulation Factors Va And VIIIa)
• Protein C, Inactivator Of Coagulation Factors Va And VIIIa
• Protein C-Nagoya
• THPH3
• THPH4
• Type I Protein C
• Vitamin K-Dependent Protein C

Description

From NCBI Gene: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]

Attributes

QA State

Under Review

Type

Protein

HGNC Name

PROC