Aliases

• 72 kDa ICln-binding protein
• EC 2.1.1.-,EC 2.1.1.125
• HMT1 hnRNP methyltransferase-like 5
• HRMT1L5
• Histone-arginine N-methyltransferase PRMT5
• IBP72
• JBP1
• Jak-binding protein 1
• PRMT5
• SKB1
• SKB1 homolog
• SKB1 homolog (S. pombe)
• SKB1Hs
• Shk1 kinase-binding protein 1 homolog
• histone-arginine N-methyltransferase PRMT5
• jak-binding protein 1
• protein arginine N-methyltransferase 5
• protein arginine methyltransferase 5
• shk1 kinase-binding protein 1 homolog
• skb1 (S. pombe) homolog

Description

From NCBI Gene: This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Attributes

QA State

Under Review

Type

Gene

HGNC Name

PRMT5