PPBP

Aliases:
This biomarker is also known as:
  • small inducible cytokine subfamily B, member 7
  • connective tissue-activating peptide III
  • LDGF
  • B-TG1
  • platelet basic protein
  • thrombocidin 2
  • low-affinity platelet factor IV
  • b-TG1
  • thromboglobulin, beta-1
  • PBP
  • CTAP3
  • LA-PF4
  • small inducible cytokine B7
  • neutrophil-activating peptide 2
  • MDGF
  • TGB
  • THBGB
  • NAP-2-L1
  • macrophage-derived growth factor
  • Beta-TG
  • CTAPIII
  • PPBP
  • pro-platelet basic protein
  • neutrophil-activating peptide-2
  • thrombocidin 1
  • leukocyte-derived growth factor
  • TGB1
  • SCYB7
  • NAP-2
  • CXCL7
  • THBGB1
  • CXC chemokine ligand 7
  • pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
  • TC2
  • beta-thromboglobulin
  • CTAP-III
  • TC1

Description…

CTAP-III (officially named PPBP) is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: PPBP

The following organs have data associated with this biomarker…

Attributes

Phase: 3
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0