PPBP

Basics
Organs
Studies
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Aliases:

This biomarker is also known as:

small inducible cytokine subfamily B, member 7
connective tissue-activating peptide III
LDGF
B-TG1
platelet basic protein
thrombocidin 2
low-affinity platelet factor IV
b-TG1
thromboglobulin, beta-1
PBP
CTAP3
LA-PF4
small inducible cytokine B7
neutrophil-activating peptide 2
MDGF
TGB
THBGB
NAP-2-L1
macrophage-derived growth factor
Beta-TG
CTAPIII
PPBP
pro-platelet basic protein
neutrophil-activating peptide-2
thrombocidin 1
leukocyte-derived growth factor
TGB1
SCYB7
NAP-2
CXCL7
THBGB1
CXC chemokine ligand 7
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
TC2
beta-thromboglobulin
CTAP-III
TC1

Description…

CTAP-III (officially named PPBP) is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.

Datasets

There are no datasets associated with this biomarker.

Attributes

QA State:	Curated
Type:	Protein
HGNC Name:	PPBP

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase:	3
QA State:	Curated

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.