PNP

Aliases:
This biomarker is also known as:
  • MGC125916
  • NP
  • nucleoside phosphorylase
  • PNP
  • FLJ97288
  • PRO1837
  • MGC125915
  • MGC117396
  • purine nucleoside phosphorylase
  • FLJ94043
  • PUNP
  • FLJ97312

Description…

PNP, a cytoplasmic protein, is an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Defects in PNP are the cause of purine nucleoside phosphorylase deficiency (PNP deficiency) which leads to a severe T-cell immunodeficiency with neurologic disorder in children. PNP mutations also affect B-cell immunity and antibody responses.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: PNP

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0