NLRP1

Aliases
  • CARD7
  • CIDED
  • CLR17.1
  • Caspase Recruitment Domain Protein 7
  • Caspase Recruitment Domain-Containing Protein 7
  • DEFCAP
  • DEFCAP-L/S
  • Death Effector Filament-Forming Ced-4-Like Apoptosis Protein
  • KIAA0926
  • Leucine Rich Repeat And Pyrin Domain Containing 1
  • NAC
  • NACHT, LRR And PYD Containing Protein 1
  • NACHT, LRR And PYD Domains-Containing Protein 1
  • NACHT, Leucine Rich Repeat And PYD (Pyrin Domain) Containing 1
  • NACHT, Leucine Rich Repeat And PYD Containing 1
  • NALP1
  • NLRP1
  • Nucleotide-Binding Domain And Caspase Recruitment Domain
  • Nucleotide-Binding Oligomerization Domain
  • Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin Domain Containing 1
  • PP1044
  • SLEV1
  • VAMAS1
Description
From NCBI Gene: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Attributes
QA State
Curated
Type
Gene
HGNC Name
NLRP1
Certifications
  • None
QA State for Prostate
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.