NCOA2

Aliases:
This biomarker is also known as:
  • Glucocorticoid Receptor Interacting Protein 1
  • Glucocorticoid Receptor-Interacting Protein-1
  • Nuclear Receptor Coactivator 2
  • SRC2
  • EC 2.3.1.48
  • HTIF2
  • Transcriptional Intermediary Factor 2
  • Class E Basic Helix-Loop-Helix Protein 75
  • P160 Steroid Receptor Coactivator 2
  • TIF2
  • NCoA-2
  • KAT13C
  • GRIP1
  • NCOA2
  • BHLHE75

Description…

From NCBI Gene: The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type:
HGNC Name:

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0