MYO5A
- Aliases
-
- Dilute myosin heavy chain, non-muscle
- GS1
- MYH12
- MYO5
- MYO5A
- MYR12
- Myosin heavy chain 12
- Myosin-12
- Myoxin
- dilute myosin heavy chain, non-muscle
- myosin V
- myosin VA (heavy chain 12, myoxin)
- myosin VA (heavy polypeptide 12, myoxin)
- myosin, heavy polypeptide kinase
- myosin-12
- myosin-Va
- myoxin
- unconventional myosin-Va
- Description
- The MYO5A gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. The MYO5A protein functions as a processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. MYO5A is also involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. Different isoforms, encoded by alternatively spliced transcript variants, have been reported.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- MYO5A
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.