MPO

Aliases
  • MPO
  • myeloperoxidase
Description
Myeloperoxidase (MPO) is a lysosomal heme protein found at chromosomal location 17q23.1. It is produced as a single chain precursor that is cleaved into two parts, a light chain and a heavy chain. The mature form of MPO is a tetramer made up of 2 light chains and 2 heavy chains. MPO is synthesized during myeloid differentiation and comprises the major component of neutrophil azurophilic granules. It is part of the host defense system of polymorphonuclear leukocytes. The production of hypohalous acids by MPO is responsible for microbicidal activity against a wide range of organisms.
Attributes
QA State
Under Review
Type
Protein
HGNC Name
MPO
Certifications
  • None
QA State for Breast
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

Certifications
  • None
QA State for Ovary
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.