MPO

Aliases:
This biomarker is also known as:
  • MPO
  • myeloperoxidase

Description…

Myeloperoxidase (MPO) is a lysosomal heme protein found at chromosomal location 17q23.1. It is produced as a single chain precursor that is cleaved into two parts, a light chain and a heavy chain. The mature form of MPO is a tetramer made up of 2 light chains and 2 heavy chains. MPO is synthesized during myeloid differentiation and comprises the major component of neutrophil azurophilic granules. It is part of the host defense system of polymorphonuclear leukocytes. The production of hypohalous acids by MPO is responsible for microbicidal activity against a wide range of organisms.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: MPO

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0