MIF
Aliases:
This biomarker is also known as:- Glycosylation-inhibiting factor
- phenylpyruvate tautomerase
- MIF
- MMIF
- L-dopachrome tautomerase
- L-dopachrome isomerase
- macrophage migration inhibitory factor (glycosylation-inhibiting factor)
- macrophage migration inhibitory factor
- GLIF
- GIF
Description…
MIF, a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation, plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. MIF is also closely related to tumorigenesis.
Datasets
There are no datasets associated with this biomarker.
Attributes
| QA State: | Curated |
|---|---|
| Type: | Protein |
| HGNC Name: | MIF |
The following organs have data associated with this biomarker…
Attributes
| Phase: | 1 |
|---|---|
| QA State: | Under Review |
Attributes
| Phase: | 3 |
|---|---|
| QA State: | Curated |
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.
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- HGNC entry for macrophage migration inhibitory factor (glycosylation-inhibiting factor) MIF
- KEGG entry 4282 for human macrophage migration inhibitory factor (glycosylation-inhibiting factor) MIF
- Entrez Protein Reference Sequence for macrophage migration inhibitory factor [Homo sapiens]
- UniProtKB/Swiss-Prot entry P14174 for MIF_HUMAN