MCAM

Aliases:
This biomarker is also known as:
  • CD146
  • melanoma-associated antigen MUC18
  • S-endo 1 endothelial-associated antigen
  • Cell surface glycoprotein P1H12
  • cell surface glycoprotein P1H12
  • Melanoma-associated antigen A32
  • melanoma cell adhesion molecule
  • Melanoma cell adhesion molecule
  • melanoma-associated antigen A32
  • melanoma adhesion molecule
  • MUC18
  • CD146 antigen
  • Melanoma-associated antigen MUC18
  • Gicerin
  • cell surface glycoprotein MUC18
  • MCAM

Description…

From UniProtKB/Swiss-Prot: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Glycomic
HGNC Name: MCAM

The following organs have data associated with this biomarker…

Attributes

Phase: 1
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Attributes

Phase: 2
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Attributes

Phase: 1
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0