LZTS1
- Aliases
-
- F37
- F37/Esophageal cancer-related gene-coding leucine-zipper motif
- F37/esophageal cancer-related gene-coding leucine-zipper motif
- FEZ1
- Fez1
- LZTS1
- Q9Y250
- leucine zipper putative tumor suppressor 1
- leucine zipper, putative tumor suppressor 1
- Description
- LZTS1 is a tumor suppressor protein that is widely expressed in normal tissues. It is involved in regulating cell growth and is also thought to interact with the active CDC2-cyclin B1 complex and contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer, and this gene is located on 8p22.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- LZTS1
- Certifications
-
- None
- QA State for Ovary
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.