LHB
Aliases:
This biomarker is also known as:- Lutropin beta chain
- lutropin subunit beta
- LSH-beta
- LSH-B
- luteinizing hormone beta polypeptide
- hLHB
- LH-B
- Luteinizing hormone subunit beta
- interstitial cell stimulating hormone, beta chain
- luteinizing hormone beta subunit
- CGB4
- LHB
- Lutropin
Description…
The pituitary glycoprotein hormone family includes follicle stimulating hormone (FSH), luteinizing hormone (LH), chorionic gonadotropin (CG), and thyroid-stimulating hormone (TSH). All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. LHB, the beta subunit of luteinizing hormone, confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
Datasets
There are no datasets associated with this biomarker.
Attributes
| QA State: | Curated |
|---|---|
| Type: | Protein |
| HGNC Name: | LHB |
The following organs have data associated with this biomarker…
Attributes
| Phase: | 3 |
|---|---|
| QA State: | Curated |
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.