Aliases

• CP64
• L-PLASTIN
• L-plastin
• L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P)
• LC64P
• LCP-1
• LCP1
• LPL
• Lymphocyte cytosolic protein 1
• Lymphocyte cytosolic protein-1 (plasmin)
• PLS2
• bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin))
• lymphocyte cytosolic protein 1 (L-plastin)
• plastin 2
• plastin-2

Description

From NCBI Gene: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008]

Attributes

QA State

Under Review

Type

Gene

HGNC Name

LCP1