KRAS

Aliases:
This biomarker is also known as:
  • KRAS
  • RASK2
  • KI-RAS
  • transforming protein p21
  • KRAS1
  • K-RAS4A
  • C-K-RAS
  • NS3
  • K-ras p21 protein
  • oncogene KRAS2
  • Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog
  • c-K-ras2 protein
  • K-RAS2B
  • NS
  • cellular c-Ki-ras2 proto-oncogene
  • c-Kirsten-ras protein
  • KRAS2
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • PR310 c-K-ras oncogene
  • K-RAS2A
  • K-RAS4B

Description…

The KRAS gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Proteomic
HGNC Name: KRAS

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0