PSA

Aliases:
This biomarker is also known as:
  • KLK3 (PSA)
  • Semenogelase
  • seminin
  • EC 3.4.21.77
  • Kallikrein-3
  • KLK3
  • prostate specific antigen
  • KLK2A1
  • prostate-specific antigen
  • kallikrein-related peptidase 3
  • hK3
  • P-30 antigen
  • PSA
  • kallikrein 3, (prostate specific antigen)
  • Gamma-seminoprotein
  • Seminin
  • kallikrein-3
  • gamma-seminoprotein
  • semenogelase
  • APS

Description…

KLK3, also known as PSA, or prostate specific antigen, a member of the kallikrein subgroup of serine proteases, is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Kallikreins are increasingly thought to be involved in carcinogenesis, and many act as cancer biomarkers. The product of the KLK3 gene is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum. KLK3, or PSA, is well known for its role in diagnosing and monitoring prostate cancer. There are several isoforms of KLK3, generated by alternate splicing and transcript variants.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Proteomic
HGNC Name: KLK3

The following organs have data associated with this biomarker…

Attributes

Phase: 3
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Attributes

Phase: 1
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0