IMPDH2

Aliases:
This biomarker is also known as:
  • IMPD 2
  • IMP (inosine monophosphate) dehydrogenase 2
  • IMPDH 2
  • IMPDH
  • IMPD2
  • inosine monophosphate dehydrogenase type II
  • EC 1.1.1.205
  • IMP oxireductase 2
  • IMP (inosine 5'-monophosphate) dehydrogenase 2
  • IMPDH-II
  • IMPDH2
  • IMP dehydrogenase 2
  • inosine 5' phosphate dehydrogenase 2
  • inosine-5'-monophosphate dehydrogenase 2

Description…

The enzyme IMPDH2 catalyzes the rate-limiting step of conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed step in the de novo synthesis of guanine nucleotides. Therefore IMPDH2 is involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It is also thought to be involvedmin the development of malignancy and the growth progression of some tumors.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: IMPDH2

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0