IL6

Aliases:
This biomarker is also known as:
  • IL6
  • HGF
  • BSF2
  • B-cell stimulatory factor 2
  • B-cell differentiation factor
  • CDF
  • B cell stimulatory factor-2
  • CTL differentiation factor
  • interleukin 6 (interferon, beta 2)
  • IL-6
  • Hybridoma growth factor
  • Interleukin 6
  • BSF-2
  • HSF
  • IFNB2
  • Interferon beta-2
  • IFN-beta-2

Description…

Interleukin 6 (IL6) is a cytokine that is involved in inflammation and the maturation of B cells as well as induction of the acute phase response. In addition to inducing myeloma and plasmacytoma growth and nerve cell differentiation, it also plays an important role in the differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. The IL6 protein is produced mainly at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The IL6 gene is involved in many inflammation-associated disease states, including diabetes mellitus, where it acts on insulin resistance, and systemic juvenile rheumatoid arthritis. IL6 is discharged into the bloodstream after muscle contraction.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Proteomic
HGNC Name: IL6

The following organs have data associated with this biomarker…

Attributes

Phase: 2
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Attributes

Phase: 2
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0