IGFBP2
Aliases:
This biomarker is also known as:- IGF-binding protein 2
- IGFBP2
- IGF-BP53
- IBP2
- IGFBP-2
- BP2
- IBP-2
- Insulin-like growth factor-binding protein 2
Description…
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Insulin-like growth factor binding protein 2 (IGFBP2) is overexpressed in ovarian malignant tissues and in the serum and cystic fluid of ovarian cancer patients, suggesting an important role of IGFBP2 in the biology of ovarian cancer.
Datasets
There are no datasets associated with this biomarker.
Attributes
| QA State: | Curated |
|---|---|
| Type: | Protein |
| HGNC Name: | IGFBP2 |
The following organs have data associated with this biomarker…
Attributes
| Phase: | 2 |
|---|---|
| QA State: | Under Review |
Attributes
| Phase: | 2 |
|---|---|
| QA State: | Under Review |
Attributes
| Phase: | 2 |
|---|---|
| QA State: |
Attributes
| Phase: | 3 |
|---|---|
| QA State: | Curated |
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.
- Entrez Protein Reference Sequence for human insulin-like growth factor-binding protein 2 precursor IGFBP2
- KEGG entry 3485 for human insulin-like growth factor binding protein 2 IGFBP2
- HGNC entry for human insulin-like growth factor binding protein 2 IGFBP2
- UniProtKB/Swiss-Prot entry for P18065 (IBP2_HUMAN)