IGFBP1
Aliases:
This biomarker is also known as:- AFBP
- IGFBP1
- Placental protein 12
- insulin-like growth factor binding protein 1
- IBP-1
- IBP1
- IGFBP-1
- hIGFBP-1
- IGF-binding protein 1
- PP12
- IGF-BP25
- alpha-pregnancy-associated endometrial globulin
Description…
IGFBP1, a secreted protein, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. IGFBP1 promotes cell migration.
Datasets
There are no datasets associated with this biomarker.
Attributes
| QA State: | Curated |
|---|---|
| Type: | Protein |
| HGNC Name: | IGFBP1 |
The following organs have data associated with this biomarker…
Attributes
| Phase: | 2 |
|---|---|
| QA State: | Under Review |
Attributes
| Phase: | 3 |
|---|---|
| QA State: | Curated |
Attributes
| Phase: | 2 |
|---|---|
| QA State: |
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.
- Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens.
- Concurrent cytogenetic, interphase fluorescence in situ hybridization and DNA flow cytometric analyses of a carcinoma ex-pleomorphic adenoma of parotid gland.
- Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer.
- UniProtKB/Swiss-Prot entry for P08833 (IBP1_HUMAN)
- KEGG entry for human insulin-like growth factor binding protein 1 IGFBP1
- Entrez Protein Reference Sequence for insulin-like growth factor-binding protein 1 precursor [Homo sapiens]
- HGNC entry for human insulin-like growth factor binding protein 1 IGFBP1