HSPB8

Aliases:
This biomarker is also known as:
  • CMT2L
  • DHMN2
  • alpha-crystallin C chain
  • Alpha-crystallin C chain
  • E2IG1
  • HMN2A
  • HSPB8
  • H11
  • HspB8
  • HMN2
  • CRYAC
  • heat shock 22kDa protein 8
  • heat shock 27kDa protein 8
  • E2-induced gene 1 protein
  • small stress protein-like protein HSP22
  • Small stress protein-like protein HSP22
  • HSP22
  • heat shock protein beta-8
  • protein kinase H11
  • Protein kinase H11

Description…

From NCBI Gene: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Gene
HGNC Name: HSPB8

The following organs have data associated with this biomarker…

Attributes

Phase: 1
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0