HMGB1

Aliases:
This biomarker is also known as:
  • SBP-1
  • Sulfoglucuronyl carbohydrate binding protein
  • Amphoterin
  • HMG3
  • High mobility group protein B1
  • HMG-1
  • high-mobility group box 1
  • high-mobility group (nonhistone chromosomal) protein 1
  • high mobility group box 1
  • high mobility group protein 1
  • HMGB1
  • DKFZp686A04236
  • HMG1

Description…

Nuclear protein HMGB1 is a DNA-binding protein that associates with chromatin and has the ability to bend DNA. It binds preferentially single-stranded DNA. HMGB1 is involved in V(D)J recombination by acting as a cofactor of the RAG complex. It acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS).

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: HMGB1

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0