Aliases

• HLA G antigen
• HLA class I histocompatibility antigen, alpha chain G
• HLA class I molecule
• HLA-6.0
• HLA-G
• HLA-G histocompatibility antigen, class I, G
• HLAG
• MHC class I antigen G
• MHC-G
• b2 microglobulin
• major histocompatibility complex, class I, G

Description

From NCBI Gene: HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Attributes

QA State

Under Review

Type

Gene

HGNC Name

HLA-G