GSTZ1

Aliases:
This biomarker is also known as:
  • glutathione S-aryltransferase
  • GSTZ1
  • EC 5.2.1.2
  • MAAI
  • glutathione s-transferase Zeta 1
  • glutathione S-alkyltransferase
  • MAI
  • maleylacetoacetate isomerase
  • S-(hydroxyalkyl)glutathione lyase
  • glutathione transferase zeta 1
  • EC 2.5.1.18
  • Glutathione S-transferase zeta 1
  • maleylacetone isomerase
  • GSTZ1-1
  • glutathione S-aralkyltransferase

Description…

The GSTZ1 gene product, glutathione transferase zeta 1, is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is also involved in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: GSTZ1

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0