GDF15

Aliases:
This biomarker is also known as:
  • NSAID-regulated gene 1 protein
  • NSAID-activated gene 1 protein
  • PTGFB
  • MIC-1
  • GDF15
  • MIC1
  • NRG-1
  • GDF-15
  • NAG-1
  • prostate differentiation factor
  • growth differentiation factor 15
  • Placental bone morphogenetic protein
  • PLAB
  • Macrophage inhibitory cytokine 1
  • Placental TGF-beta
  • PDF
  • Prostate differentiation factor

Description…

GDF15, also known as macrophage inhibitory cytokine 1, or MIC1, is a bone morphogenetic protein (BMP) belonging to the transforming growth factor-beta (TGF-beta) superfamily. The bone morphogenetic proteins regulate tissue differentiation and maintenance. GDF15 is a secreted protein that is highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. Bone morphogenetic protein precursor molecules are cleaved at a dibasic site to release C-terminal domains with 7 conserved cysteines in the mature protein.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: GDF15

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0