GCLM

Aliases:
This biomarker is also known as:
  • glutamate--cysteine ligase regulatory subunit
  • gamma-ECS regulatory subunit
  • glutamate--cysteine ligase modifier subunit
  • GLCLR
  • glutamate-cysteine ligase, modifier subunit
  • gamma-glutamylcysteine synthetase regulatory subunit
  • glutamate-cysteine ligase modifier subunit delta2 alternative splicing
  • Glutamate--cysteine ligase modifier subunit
  • Gamma-glutamylcysteine synthetase regulatory subunit
  • GCS light chain
  • Gamma-ECS regulatory subunit
  • gamma-glutamylcysteine synthetase
  • GCLM
  • GSC light chain
  • glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD)
  • glutamate-cysteine ligase regulatory protein

Description…

From NCBI Gene: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: GCLM

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0