FAS

Aliases:
This biomarker is also known as:
  • FASTM
  • FAS 827dupA
  • APT1
  • tumor necrosis factor receptor superfamily member 6
  • apoptosis-mediating surface antigen FAS
  • CD95 antigen
  • Fas (TNF receptor superfamily, member 6)
  • TNFRSF6
  • FAS
  • Delta Fas/APO-1/CD95
  • Apo-1 antigen
  • FAS (Ab2)
  • Fas AMA
  • APO-1
  • FASLG receptor
  • ALPS1A
  • CD95
  • tumor necrosis factor receptor superfamily, member 6
  • FAS1
  • FAS (Ab1)
  • APO-1 cell surface antigen
  • Apoptosis-mediating surface antigen FAS
  • apoptosis antigen 1

Description…

FAS is a member of the TNF-receptor superfamily. The FAS protein is a receptor for TNFSF6/FASLG and has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: FAS

The following organs have data associated with this biomarker…

Attributes

Phase: 2
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Attributes

Phase: 3
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0