Aliases

• E74-like factor 5
• E74-like factor 5 (ets domain transcription factor)
• ELF5
• ESE-2
• ESE2
• ETS-related transcription factor Elf-5
• Epithelium-restricted ESE-1-related Ets factor
• Epithelium-specific Ets transcription factor 2
• epithelium-restricted ESE-1-related Ets factor
• epithelium-specific Ets transcription factor 2

Description

From NCBI Gene: The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]

Attributes

QA State

Under Review

Type

Gene

HGNC Name

ELF5