DUSP22
- Aliases
-
- DUSP22
- EC 3.1.3.16,EC 3.1.3.48
- JKAP
- JNK-stimulating phosphatase 1
- JNK-stimulatory phosphatase-1
- JSP-1
- JSP1
- LMW-DSP2
- LMWDSP2
- Low molecular weight dual specificity phosphatase 2
- MAP kinase phosphatase x
- MKP-x
- MKPX
- Mitogen-activated protein kinase phosphatase x
- VHX
- dual specificity phosphatase 22
- dual specificity protein phosphatase 22
- homolog of mouse dual specificity phosphatase LMW-DSP2
- low molecular weight dual specificity phosphatase 2
- mitogen-activated protein kinase phosphatase x
- Description
- From NCIB Gene: Enables non-membrane spanning protein tyrosine phosphatase activity and protein tyrosine kinase binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; negative regulation of focal adhesion assembly; and negative regulation of non-membrane spanning protein tyrosine kinase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in plasma membrane. Part of cytoplasm; filamentous actin; and leading edge of lamellipodium. [provided by Alliance of Genome Resources, Nov 2021] From UniProtKB/Swiss-Prot: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity).
Attributes
- QA State
- Under Review
- Type
- Gene
- HGNC Name
- DUSP22
- Certifications
-
- None
- QA State for Prostate
- Under Review
Non-Public Biomarker
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Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.