CYP24A1
- Aliases
-
- 1,25-@dihydroxyvitamin D3 24-hydroxylase
- 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
- 24-OHase
- CP24
- CYP24
- CYP24A1
- Cytochrome P450 24A1
- Cytochrome P450-CC24
- EC 1.14.13.126
- HCAI
- P450-CC24
- Vitamin D(3) 24-hydroxylase
- cytochrome P450, family 24, subfamily A, polypeptide 1
- cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
- exo-mitochondrial protein
- vitamin D 24-hydroxylase
- Description
- The CYP24A1 protein is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP24A1 is involved in maintaining calcium homeostasis and catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and calcitriol (1-alpha,25-dihydroxyvitamin D3). Several different isoforms exist, encoded by alternatively spliced transcript variants.
Attributes
- QA State
- Under Review
- Type
- Gene
- HGNC Name
- CYP24A1
- Certifications
-
- None
- QA State for Lung
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.