CFH

Aliases:
This biomarker is also known as:
  • H Factor 1 (Complement)
  • HF2
  • HUS
  • H Factor 1
  • AHUS1
  • Adrenomedullin Binding Protein
  • FHL1
  • Beta-1H
  • Complement Factor H
  • AMBP1
  • H Factor 2 (Complement)
  • Age-Related Maculopathy Susceptibility 1
  • Beta-1-H-Globulin
  • Factor H
  • HF1
  • CFH
  • ARMD4
  • FH
  • Factor H-Like 1
  • ARMS1
  • CFHL3
  • HF

Description…

From NCBI Gene: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: CFH

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0